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Segn la Sociedad Estadounidense del Cncer American Cancer Society, los defectos en ese gen y en otro, llamado BRCA2, aumentan sustancialmente el riesgo de por vida de una mujer de contraer cncer de mama y de ovario, a alrededor de un 60 por ciento de probabilidades de contraer cncer de mama y a un riesgo de entre el 15 y el 40 por ciento de cncer de ovario.

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